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Results for " HY-P1928 " in MedChemExpress (MCE) Product Catalog:

Inhibitors & Agonists

Cat. No. Product Name Target Research Area
  • HY-P1928
    Humanin Bcl-2 Family Neurological Disease; Endocrinology
    Humanin, an anti-apoptotic peptide of 24 amino acids, is a Bax inhibitor. Humanin prevents the translocation of Bax from cytosol to mitochondria, blocks Bax from the inactive to active conformation. Humanin is a mitochondria-associated peptide with a neuroprotective effect against AD-related neurotoxicity. Humanin also improves overall insulin sensitivity in animal. Humanin are related to aging[1][2].
    Humanin analogue, in which the serine at position 14 is replaced by glycine, names HNG[2].

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